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  2. Fidanacogene elaparvovec - Wikipedia

    en.wikipedia.org/wiki/Fidanacogene_elaparvovec

    In the US, fidanacogene elaparvovec is indicated for the treatment of adults with moderate to severe hemophilia B (congenital factor IX deficiency) who currently use factor IX prophylaxis therapy; or have current or historical life-threatening hemorrhage; or have repeated, serious spontaneous bleeding episodes; and do not have neutralizing antibodies to adeno-associated virus serotype Rh74var ...

  3. FDA approves Pfizer's first gene therapy for rare inherited ...

    www.aol.com/news/fda-approves-pfizer-first-gene...

    The gene therapy will compete with Australia-based CSL Behring’s Hemgenix, a similar treatment that won FDA approval for hemophilia B in 2022. That drug has a similar list price of $3.5 million ...

  4. Pfizer Discontinues Hemophilia Gene Therapy Beqvez As ...

    www.aol.com/finance/pfizer-discontinues...

    According to multiple media reports on Thursday, Pfizer Inc. (NYSE:PFE) has terminated the global development and commercialization of its hemophilia B gene therapy, Beqvez. In April 2024, the FDA ...

  5. US FDA approves Pfizer's gene therapy for rare bleeding ... - AOL

    www.aol.com/news/us-fda-approves-pfizers-gene...

    (Reuters) -The U.S. Food and Drug Administration approved Pfizer's gene therapy for hemophilia B on Friday, the second such therapy for the rare bleeding disorder that typically requires regular ...

  6. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    In July results of a gene therapy candidate for haemophilia B called FLT180 were announced, it works using an adeno-associated virus (AAV) to restore the clotting factor IX (FIX) protein, normal levels of the protein were observed with low doses of the therapy but immunosuppression was necessitated to decrease the risk of vector-related immune ...

  7. MT-CYB - Wikipedia

    en.wikipedia.org/wiki/MT-CYB

    Location of the MT-CYB gene in the human mitochondrial genome (coral box).. Cytochrome b is a protein that in humans is encoded by the MT-CYB gene. [5] Its gene product is a subunit of the respiratory chain protein ubiquinol–cytochrome c reductase (UQCR, complex III or cytochrome bc 1 complex), which consists of the products of one mitochondrially encoded gene, MT-CYB (mitochondrial ...

  8. Pfizer's gene therapy cuts hemophilia A bleeding rate in late ...

    www.aol.com/news/pfizers-hemophilia-gene-therapy...

    The data takes Pfizer one step closer to securing U.S. regulatory approval for a second gene therapy to treat hemophilia. Pfizer had received the Food and Drug Administration's nod for Beqvez as a ...

  9. EU regulator backs use of Pfizer's gene therapy for rare ...

    www.aol.com/news/eu-regulator-recommends-pfizers...

    The therapy carries a price tag of $3.5 million in the U.S. - the same as Australian drugmaker CSL Ltd's rival gene therapy Hemgenix. In the EU, it will be sold under the brand name Durveqtix.

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