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Glucose 6-phosphatase-β is a ubiquitously expressed, 346-amino acid membrane protein that shares 36% sequence identity with glucose 6-phosphatase-α. Within the glucose 6-phosphatase-β enzyme, sequence alignments predict that its active site contains His167, His114, and Arg79.
English: glucose-6-phosphatase system: in the end of the gluconeogenesis glc-6-p is transported into the ER (G6PT = T1) and dephosphorylated (G6Pase). Glucose is transported out of the cell passing two glucose-transporters (GLUT7 = T3 and GLUT2). Inorg. Phosphate is transported back to the cytosol by the T2 transporter
Glucose-6-phosphatase, catalytic subunit (glucose 6-phosphatase alpha) is an enzyme that in humans is encoded by the G6PC gene. [ 5 ] [ 6 ] Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate.
Location (UCSC) PubMed search: Wikidata: View/Edit Human: View/Edit Mouse: Glucose-6-phosphatase 3, also known as glucose-6-phosphatase beta, is an ...
14378 Ensembl ENSG00000278373 ENSG00000152254 ENSMUSG00000005232 UniProt Q9NQR9 Q9Z186 RefSeq (mRNA) NM_001081686 NM_021176 NM_001289856 NM_001289857 NM_021331 RefSeq (protein) NP_001075155 NP_066999 NP_001276785 NP_001276786 NP_067306 Location (UCSC) Chr 2: 168.9 – 168.91 Mb Chr 2: 69.04 – 69.06 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Glucose-6-phosphatase 2 is an enzyme ...
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Glucose-6-phosphate exchanger SLC37A4, also known as glucose-6-phosphate translocase, is an enzyme that in humans is encoded by the SLC37A4 gene. [ 5 ] [ 6 ] [ 7 ] It consists of three subunits , each of which are vital components of the multi-enzyme Glucose-6-Phosphatase Complex (G6Pase).
This reaction converts glucose 6-phosphate to fructose 6-phosphate in preparation for phosphorylation to fructose 1,6-bisphosphate. [2] The addition of the second phosphoryl group to produce fructose 1,6-bisphosphate is an irreversible step, and so is used to irreversibly target the glucose 6-phosphate breakdown to provide energy for ATP ...