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Magnesium aspartate is a magnesium salt of aspartic acid. [1] It is used as a mineral supplement, and as an ingredient in manufacturing of cosmetics and household products. [1] As magnesium is an essential micronutrient, [2] the use of magnesium aspartate as a supplement is intended to increase magnesium levels in the body. [3] [4]
10–15% (developed world) [1] [11] and 15–45% (globally) [12] Irritable bowel syndrome ( IBS ) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain , abdominal bloating and changes in the consistency of bowel movements . [ 1 ]
Diagnosis is based on a blood level of magnesium greater than 1.1 mmol/L (2.6 mg/dL). [1] [3] It is severe if levels are greater than 2.9 mmol/L (7 mg/dL). [5] Specific electrocardiogram (ECG) changes may be present. [1] Treatment involves stopping the magnesium a person is getting. [2]
An adult body has 22–26 grams of magnesium, [15] [113] with 60% in the skeleton, 39% intracellular (20% in skeletal muscle), and 1% extracellular. [15] Serum levels are typically 0.7–1.0 mmol/L or 1.8–2.4 mEq /L. Serum magnesium levels may be normal even when intracellular magnesium is deficient.
In the table above, magnesium appears to be an anomaly as the recommended intake for adult men is 420 mg/day (women 350 mg/day) while the UL is lower than the recommended, at 350 mg. The reason is that the UL is specific to consuming more than 350 mg of magnesium all at once, in the form of a dietary supplement, as this may cause diarrhea.
Hypocitraturia or low urinary-citrate excretion (variably defined as less than 320 mg/day) can be a contributing cause of kidney stones in up to 2/3 of cases. The protective role of citrate is linked to several mechanisms; citrate reduces urinary supersaturation of calcium salts by forming soluble complexes with calcium ions and by inhibiting ...
Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
In the US, the average lifetime cost (treatment and follow-up) was $17,166 per person in 1996. The average hospital charge for sphincteroplasty was $8555 per procedure. Overall, in the US, the total charges associated with surgery increased from $34 million in 1998 to $57.5 million in 2003.
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