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Methylphosphonyl dichloride (DC) or dichloro is an organophosphorus compound. It has commercial application in oligonucleotide synthesis, [1] but is most notable as being a precursor to several chemical weapons agents. It is a white crystalline solid that melts slightly above room temperature. [2]
Methyldichlorophosphine belongs to the group of halophosphines, some of which are used as intermediates in the production of plant protection agents, stabilizers for plastics, and catalysts.
Dimethyl methylphosphonate can be prepared from trimethyl phosphite and a halomethane (e.g. iodomethane) via the Michaelis–Arbuzov reaction. [2]Dimethyl methylphosphonate is a schedule 2 chemical as it may be used in the production of chemical weapons.
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Tolperisone (trade name Mydocalm among others) is a centrally acting skeletal muscle relaxant used for the treatment of increased muscle tone associated with neurological diseases. It has been used since the 1960s. [1] [2]
It, along with methylphosphonyl difluoride (DF), was developed during the 1980s in order to replace an aging stockpile of unitary chemical weapons. [3] QL is listed as a Schedule 1 chemical by the Chemical Weapons Convention .
57 °C (135 °F; 330 K) [1] at 2 mmHg Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references
[1] [2] However, aluminum chloride often induces diarylation; a cleaner catalyst for monoarylation is stannic chloride. [2] The compound is an intermediate for the synthesis of other chemicals for instance dimethylphenylphosphine: C 6 H 5 PCl 2 + 2 CH 3 MgI → C 6 H 5 P(CH 3) 2 + 2 MgICl. Many tertiary phosphines can be prepared by this route. [3]