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Research regarding late-life depression often focuses on late-onset depression, which is defined as a major depressive episode occurring for the first time in an older person (various sources define this threshold differently, typically within the range of 60–65 years old). [1] [2] Late-life depression is often underdiagnosed, which is due to ...
While there are short-term performance benefits to caffeine consumption, overuse can lead to insomnia symptoms or worsen pre-existing insomnia. [138] Consuming caffeine to stay awake at night may lead to sleeplessness, anxiety, frequent nighttime awakenings, and overall poorer sleep quality. [139]
If PKA or protein synthesis inhibition occurs at certain moments during sleep, memory consolidation can be disrupted [citation needed]. In addition, mice with genetic inhibition of PKA have been shown to have long-term memory deficits. [48] Thus, sleep deprivation may act through the inhibition of these protein synthesis pathways.
In their lifetime, 20% to 25% of women and 7% to 12% of men will have a major depressive episode. [35] The peak period of development is between the ages of 25 and 44. [3] The onset of major depressive episodes or MDD often occurs in people in their mid-20s and less often in those over 65.
In fact, many studies have found a bidirectional relationship between stress and sleep. This means that sleep quality can affect stress levels, and stress levels can affect sleep quality. Sleep change depends on the type of stressor, sleep perception, related psychiatric conditions, environmental factors, and physiological limits. [5] [6] [4] [7]
Depression is sometimes associated with insomnia (difficulty in falling asleep, early waking, or waking in the middle of the night). The combination of these two results, depression and insomnia, will only worsen the situation. Hence, good sleep hygiene is important to help break this vicious circle. [183]
Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1 ...
Minor depressive disorder, also known as minor depression, is a mood disorder that does not meet the full criteria for major depressive disorder but at least two depressive symptoms are present for a long time. These symptoms can be seen in many different psychiatric and mental disorders, which can lead to more specific diagnoses of an ...
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