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On its way, the fluid passes through the lymph nodes, small nodular organs located throughout the body but concentrated in certain areas such as the armpits or groin. These lymph nodes are also known as glands or lymphoid tissue. If they detect something foreign passing through them, they enlarge. This is called lymphadenopathy or swollen glands.
Generalized lymphadenopathy is swollen lymph glands in many areas of the body. [1]Usually this is in response to a body-wide infectious disease such as influenza and will go away once the person has recovered, but sometimes it can persist long-term, even when there is no obvious cause of disease.
Inguinal lymphadenopathy causes swollen lymph nodes in the groin area. It can be a symptom of infective or neoplastic processes. It can be a symptom of infective or neoplastic processes. Infective aetiologies include Tuberculosis, HIV , non-specific or reactive lymphadenopathy to recent lower limb infection or groin infections.
Size, where lymphadenopathy in adults is often defined as a short axis of one or more lymph nodes is greater than 10mm. [29] By extent: Localized lymphadenopathy: due to localized spot of infection; e.g., an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up
The presence of swollen inguinal lymph nodes is an important clinical sign because lymphadenopathy (swelling) may indicate an infection, or spread as a metastasis from cancers, such as anal cancer and vulvar cancer. Inguinal lymph nodes may normally be up to 2 cm. [1] The cut-off value for normal sized inguinal nodes is up to 10 mm. [6]
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