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C. Garrison Fathman is a Professor of Medicine and Division Chief of Immunology and Rheumatology at Stanford University School of Medicine.He is also the Associate Director of the Institute for Immunity, Transplantation and Infection and Director of the Center for Clinical Immunology at Stanford University.
As of 2024, she is an emeritus professor at Scripps Research, and serves on the advisory boards of the La Jolla Institute for Immunology and the San Diego Biomedical Research Institute. [3] [4] Her research has focused on immune tolerance and autoimmunity, particularly type 1 diabetes, as well as the immune response to tumors.
Immune tolerance encompasses the range of physiological mechanisms by which the body reduces or eliminates an immune response to particular agents. It is used to describe the phenomenon underlying discrimination of self from non-self, suppressing allergic responses, allowing chronic infection instead of rejection and elimination, and preventing ...
Matzinger is chief of the T-Cell Tolerance and Memory Section at the U.S. National Institute of Allergy and Infectious Diseases (NIAID). [6] The lab has been referred to as the "Ghost Lab" for Matzinger's choice to conduct the first nine months of her research alone with a focus on chaos theory.
Immune tolerance therapies seek to reset the immune system so that the body stops mistakenly attacking its own organs or cells in autoimmune disease or accepts foreign tissue in organ transplantation. [66] A recent [when?] therapeutic approach is the infusion of regulatory immune cells into transplant recipients. The transfer of regulatory ...
But if there was a decent coverage of this topic then immune tolerance would be a massive article (with 30 000 peer-reviewed articles written on it, the topic is huge and varied). I think immune tolerance should basically remain an overview article, with links to the specific forms of immune tolerance, such as central tolerance, negative ...
Sir Peter Brian Medawar OM CH CBE FRS (/ ˈ m ɛ d ə w ər /; 28 February 1915 – 2 October 1987) [1] was a British biologist and writer, whose works on graft rejection and the discovery of acquired immune tolerance have been fundamental to the medical practice of tissue and organ transplants.
APS-1 is due to problems with immune tolerance. [11] APS-1 causes considerable reactions with both interferon omega and interferon alpha. [4] [12] There may also be a reaction against interleukin 22. [4] This leads to damage to endocrine organs. [4]