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Bronchial thermoplasty [1] is a treatment for severe asthma approved by the FDA in 2010 involving the delivery of controlled, therapeutic radiofrequency energy to the airway wall, thus heating the tissue and reducing the amount of smooth muscle present in the airway wall.
Asthma is a common long-term inflammatory disease of the airways of the lungs. [4] Asthma occurs when allergens, pollen, dust, or other particles, are inhaled into the lungs, causing the bronchioles to constrict and produce mucus, which then restricts oxygen flow to the alveoli.
Airway remodelling is a multifaceted process involving multiple airway tissues. These include goblet cell hyperplasia, leading to increased mucus production, and airway smooth muscle hypertrophy (or smooth muscle cell hyperplasia), leading to the release of pro-inflammatory and pro-fibrotic messengers contributing to subepithelial fibrosis.
Examples of diseases associated with expectoration of casts, and which sometimes are labeled PB include tuberculosis, atypical mycobacterial disease, allergic bronchopulmonary aspergillosis, and asthma. When casts are very large with many branches, an abnormal communication or leakage of lymphatic fluid into the airway is often the cause.
The most common cause of this is asthma. Bronchospasm is commonly treated by oxygen therapy and bronchodilators such as albuterol . Diseases of the bronchioles include asthma , bronchiolitis obliterans , respiratory syncytial virus infections, and influenza .
This is also a shorter procedure with a single-shot circumferential approach, eliminating fluoroscopy and ancillary devices, with a universal catheter design suitable for diverse airway anatomies. Asthma and COPD are among the most prevalent chronic diseases globally, affecting over 600 million people.
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