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Many analogues of pyridine are known where N is replaced by other heteroatoms from the same column of the Periodic Table of Elements (see figure below). Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C 4 H 4 N 2), with the names pyridazine, pyrimidine, and pyrazine.
Heterocyclic rings systems that are formally derived by fusion with other rings, either carbocyclic or heterocyclic, have a variety of common and systematic names. For example, with the benzo-fused unsaturated nitrogen heterocycles, pyrrole provides indole or isoindole depending on the orientation. The pyridine analog is quinoline or isoquinoline.
Niacin, essential to many types of life, is an example of a heterocyclic amine.. Heterocyclic amines, also sometimes referred to as HCAs, are chemical compounds containing at least one heterocyclic ring, which by definition has atoms of at least two different elements, as well as at least one amine (nitrogen-containing) group.
It is the conjugate acid of pyridine. Many related cations are known involving substituted pyridines, e.g. picolines, lutidines, collidines. They are prepared by treating pyridine with acids. [3] As pyridine is often used as an organic base in chemical reactions, pyridinium salts are produced in many acid-base reactions.
Pyridyne in chemistry is the pyridine analogue of benzyne. [1] Pyridynes are the class of reactive intermediates derived from pyridine. Two isomers exist, the 2,3-pyridine (2,3-didehydropyridine) and the 3,4-pyridyne (3,4-didehydropyridine).
Names Preferred IUPAC name. Pyridin-2-amine. Other names ... It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction. [3]
Alpidem (original brand name Ananxyl)—an anxiolytic that was withdrawn from the market worldwide in 1995 due to hepatotoxicity. DS-1—a GABA A receptor positive allosteric modulator selective for the α 4 β 3 δ subtype, which is not targeted by other GABAergics such as benzodiazepines or other nonbenzodiazepines. [1] Necopidem—an ...