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Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene. [ 5 ] [ 6 ] [ 7 ] Increased expression of Ly6E is associated with poor survival outcome in multiple malignancies as determined by a survey of more than 130 published clinical studies of gene expression studies on cancer tissue samples and adjacent normal tissues. [ 8 ]
Ly6 proteins are characterized by the LU domain.Typically, they contain one LU domain, but some members of the family have multiple LU domains.The LU domain consists of 60-80 AA and contains 10 cysteines arranged in a specific pattern that allows the creation of 5 disulfide bridges which in turn allow the formation of a three-fingered (3F) structural motif.
79136 n/a Ensembl ENSG00000255552 n/a UniProt n a n/a RefSeq (mRNA) NM_001003721 NM_024123 n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human Lymphocyte antigen 6 complex, locus G6E (pseudogene) is a protein that in humans is encoded by the LY6G6E gene. Function LY6G6E belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major ...
This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...
Most often the lymphocyte count is greater than 5000 cells per microliter (μL) of blood but can be much higher. [41] The presence of lymphocytosis in a person who is elderly should raise strong suspicion for CLL, and a confirmatory diagnostic test, in particular flow cytometry should be performed unless clinically unnecessary. [42]
In adults, absolute lymphocytosis is present when the lymphocyte count is greater than 5000 per microliter (5.0 x 10 9 /L), in older children greater than 7000 per microliter and in infants greater than 9000 per microliter. [1] Lymphocytes normally represent 20% to 40% of circulating white blood cells. When the percentage of lymphocytes exceeds ...
The 35-49 age group now has the lowest estimated level of antibodies. ... Covid-19 antibody levels jump among elderly after autumn booster. Ian Jones, PA. January 18, 2023 at 7:40 AM.
The protein is 183 amino acids long and its molecular mass is 20.656. [6] The gene LYPD6B encoding the protein is located on chromosome 2 in humans. As a member of the Ly-6/uPAR family, the protein contains a disulfide β-structural core and three protruding loops. [7]
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