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  2. Cholesteryl ester - Wikipedia

    en.wikipedia.org/wiki/Cholesteryl_ester

    Cholesteryl ester is transported from high-density lipoproteins (HDLs) to low-density lipoproteins (LDLs) and very low-density lipoproteins (VLDLs) with cholesteryl ester transfer protein (CETP). [5] The decrease in cholesteryl ester can lower HDL and increase LDL, which may be an indicator of cardiovascular problems, as indicated by ...

  3. Cholesteryl ester transfer protein - Wikipedia

    en.wikipedia.org/wiki/Cholesteryl_ester_transfer...

    1071 n/a Ensembl ENSG00000087237 n/a UniProt P11597 n/a RefSeq (mRNA) NM_000078 NM_001286085 n/a RefSeq (protein) NP_000069 NP_001273014 n/a Location (UCSC) Chr 16: 56.96 – 56.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and ...

  4. CETP inhibitor - Wikipedia

    en.wikipedia.org/wiki/CETP_inhibitor

    Drugs in this class substantially increase HDL cholesterol, lower LDL cholesterol, and enhance reverse cholesterol transport. [citation needed]CETP inhibitors inhibit cholesterylester transfer protein (CETP), which normally transfers cholesterol from HDL cholesterol to very low density or low density lipoproteins (VLDL or LDL).

  5. Lipoprotein - Wikipedia

    en.wikipedia.org/wiki/Lipoprotein

    Lipoproteins are complex particles that have a central hydrophobic core of non-polar lipids, primarily cholesteryl esters and triglycerides. This hydrophobic core is surrounded by a hydrophilic membrane consisting of phospholipids, free cholesterol, and apolipoproteins.

  6. Reverse cholesterol transport - Wikipedia

    en.wikipedia.org/wiki/Reverse_cholesterol_transport

    The cholesteryl esters can be transferred, with the help of CETP (cholesterylester transfer protein) in exchange for triglycerides, to other lipoproteins (such as LDL and VLDL), and these lipoproteins can be taken up by secreting unesterified cholesterol into the bile or by converting cholesterol to bile acids.

  7. Low-density lipoprotein - Wikipedia

    en.wikipedia.org/wiki/Low-density_lipoprotein

    LDL particles are formed when triglycerides are removed from VLDL by the lipoprotein lipase enzyme (LPL) and they become smaller and denser (i.e. fewer fat molecules with same protein transport shell), containing a higher proportion of cholesterol esters. [9] [10]

  8. High-density lipoprotein - Wikipedia

    en.wikipedia.org/wiki/High-density_lipoprotein

    In humans, probably the most relevant pathway is the indirect one, which is mediated by cholesteryl ester transfer protein (CETP). [2] This protein exchanges triglycerides of VLDL against cholesteryl esters of HDL. As the result, VLDLs are processed to LDL, which are removed from the circulation by the LDL receptor pathway.

  9. Apolipoprotein - Wikipedia

    en.wikipedia.org/wiki/Apolipoprotein

    Basic amino acids important for LDL receptor binding are clustered into a surface patch on one long helix. [9] Apolipoprotein F (apoF) is one of the minor apolipoprotein in blood plasma and it is a lipid transfer inhibit protein to inhibit cholesteryl ester transfer protein-mediated transfers of cholesteryl esters and triglycerides. [10] [11]

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