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The two theories; non-adaptive, and adaptive, are used to explain the evolution of senescence, which is the decline in reproduction with age. [8] The non-adaptive theory assumes that the evolutionary deterioration of human age occurs as a result of accumulation of deleterious mutations in the germline. [8]
Selectivity theory (aging) Socioemotional selectivity theory; Stage-crisis view; Stem cell theory of aging; Stereotype embodiment theory; T. Telomere theory of aging; V.
This is an accepted version of this page This is the latest accepted revision, reviewed on 13 February 2025. Biological process of getting older This article is about ageing specifically in humans. For the ageing of whole organisms including animals, see Senescence. For other uses, see Ageing (disambiguation). Part of a series on Human growth and development Stages Gamete Zygote Embryo Fetus ...
The metabolic stability theory of aging suggests it is the cells ability to maintain stable concentration of ROS which is the primary determinant of lifespan. [37] This theory criticizes the free radical theory because it ignores that ROS are specific signalling molecules which are necessary for maintaining normal cell functions. [37]
Therefore, he suggested that aging was an evolved trait which allowed an organism's descendants to thrive. [11] 1882 August Weismann puts forward the wear and tear theory of aging independently of Wallace. [15] [16] 1889 Rejuvenation experiment conducted on himself by the French doctor Charles-Édouard Brown-Séquard. He made himself a few ...
Aging theories based on group selection; Antagonistic pleiotropy hypothesis; C. Cross-linking theory of aging; D. Disposable Soma Theory; DNA damage theory of aging; E.
All evolutionary theories of aging rest on the basic mechanisms that the force of natural selection declines with age. [19] [20] Mechanistic theories of aging can be divided into theories that propose aging is programmed, and damage accumulation theories, i.e. those that propose aging to be caused by specific molecular changes occurring over time.
Biogerontology should not be confused with geriatrics, which is a field of medicine that studies the treatment of existing disease in aging people, rather than the treatment of aging itself. There are numerous theories of aging, and no one theory has been entirely accepted.