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  2. Cerebral perfusion pressure - Wikipedia

    en.wikipedia.org/wiki/Cerebral_perfusion_pressure

    Cerebral perfusion pressure, or CPP, is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion).It must be maintained within narrow limits because too little pressure could cause brain tissue to become ischemic (having inadequate blood flow), and too much could raise intracranial pressure (ICP).

  3. Intracranial pressure - Wikipedia

    en.wikipedia.org/wiki/Intracranial_pressure

    Intracranial hypertension (IH), also called increased ICP (IICP) or raised intracranial pressure (RICP), refers to elevated pressure in the cranium. 20–25 mmHg is the upper limit of normal at which treatment is necessary, though it is common to use 15 mmHg as the threshold for beginning treatment.

  4. Pressure reactivity index - Wikipedia

    en.wikipedia.org/wiki/Pressure_reactivity_index

    Traumatic brain injury can cause dangerously raised intracranial pressure. Pressure reactivity index or PRx is a tool for monitoring cerebral autoregulation in the intensive care setting for patients with severe traumatic brain injury or subarachnoid haemorrhage, in order to guide therapy to protect the brain from dangerously high or low cerebral blood flow.

  5. Cerebral edema - Wikipedia

    en.wikipedia.org/wiki/Cerebral_edema

    [3] [44] [45] Bolus doses, particularly at higher concentrations, for example 23.4%, are effective at reducing ICP and improving cerebral perfusion pressure. [ 44 ] [ 46 ] In traumatic brain injuries , a responsiveness to hypertonic saline lasting greater than 2 hours was associated with decreased chance of death and improved neurologic ...

  6. Normal pressure hydrocephalus - Wikipedia

    en.wikipedia.org/wiki/Normal_pressure_hydrocephalus

    Incidence is estimated to 0.3–3% in patients older than 60 years and raising with older age. [38] Its prevalence is reported to be less than 1% in persons under the age of 65, and up to 3% for persons aged 65 or older. No difference in incidence is seen between men and women or amongst differing ethnicities.

  7. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    For most substances presented, the optimal levels are the ones normally found in the population as well. More specifically, optimal levels are generally close to a central tendency of the values found in the population. However, usual and optimal levels may differ substantially, most notably among vitamins and blood lipids, so these tables give ...

  8. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    It most often begins in people over 65 years of age, although up to 10% of cases are early-onset impacting those in their 30s to mid-60s. [27] [4] It affects about 6% of people 65 years and older, [16] and women more often than men. [28] The disease is named after German psychiatrist and pathologist Alois Alzheimer, who first described it in ...

  9. Blood pressure - Wikipedia

    en.wikipedia.org/wiki/Blood_pressure

    There is an ongoing medical debate over what is the optimal level of blood pressure to target when using drugs to lower blood pressure with hypertension, particularly in older people. [ 13 ] Blood pressure fluctuates from minute to minute and normally shows a circadian rhythm over a 24-hour period, [ 14 ] with highest readings in the early ...