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  2. Evolution of ageing - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_ageing

    The somatic mutation theory of ageing states that accumulation of mutations in somatic cells is the primary cause of aging. A comparison of somatic mutation rate across several mammal species found that the total number of accumulated mutations at the end of lifespan was roughly equal across a broad range of lifespans. [ 16 ]

  3. Human vestigiality - Wikipedia

    en.wikipedia.org/wiki/Human_vestigiality

    Arrows show the vestigial structure called Darwin's tubercle. In the context of human evolution, vestigiality involves those traits occurring in humans that have lost all or most of their original function through evolution. Although structures called vestigial often appear functionless, they may retain lesser functions or develop minor new ones.

  4. Vestigiality - Wikipedia

    en.wikipedia.org/wiki/Vestigiality

    In humans, the vermiform appendix is sometimes called a vestigial structure as it has lost much of its ancestral digestive function.. Vestigiality is the retention, during the process of evolution, of genetically determined structures or attributes that have lost some or all of the ancestral function in a given species. [1]

  5. Biogerontology - Wikipedia

    en.wikipedia.org/wiki/Biogerontology

    Genetic theories of aging propose that aging is programmed within each individual's genes. According to this theory, genes dictate cellular longevity. Programmed cell death, or apoptosis, is determined by a "biological clock" via genetic information in the nucleus of the cell. Genes responsible for apoptosis provide an explanation for cell ...

  6. Mutation accumulation theory - Wikipedia

    en.wikipedia.org/wiki/Mutation_accumulation_theory

    The mutation accumulation theory of aging was first proposed by Peter Medawar in 1952 as an evolutionary explanation for biological aging and the associated decline in fitness that accompanies it. [1] Medawar used the term 'senescence' to refer to this process.

  7. Genetics of aging - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_aging

    Other genes regulate aging in yeast by increasing the resistance to oxidative stress. Superoxide dismutase, a protein that protects against the effects of mitochondrial free radicals, can extend yeast lifespan in stationary phase when overexpressed. In higher organisms, aging is likely to be regulated in part through the insulin/IGF-1 pathway.

  8. Psychological adaptation - Wikipedia

    en.wikipedia.org/wiki/Psychological_adaptation

    These additional EPMs are the by-product traits of a species’ evolutionary development (see spandrels), as well as the vestigial traits that no longer benefit the species’ fitness. It can be difficult to tell whether a trait is vestigial or not, so some literature is more lenient and refers to vestigial traits as adaptations, even though ...

  9. Atavism - Wikipedia

    en.wikipedia.org/wiki/Atavism

    A number of traits can vary as a result of shortening of the fetal development of a trait or by prolongation of the same. In such a case, a shift in the time a trait is allowed to develop before it is fixed can bring forth an ancestral phenotype. [5] Atavisms are often seen as evidence of evolution. [6]