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Pseudoephedrine is widely available over-the-counter (OTC) in both single-drug and combination preparations. [30] [22] [13] [2] Availability of pseudoephedrine has been restricted starting in 2005 as it can be used to synthesize methamphetamine. [13] [2] Phenylephrine has replaced pseudoephedrine in many over-the-counter oral decongestant ...
Besides hypertension, common side-effects include sleeplessness, anxiety, dizziness, excitability, and nervousness. Topical nasal or ophthalmic decongestants quickly develop tachyphylaxis (a rapid decrease in the response to a drug after repeated doses over a short period of time). Long-term use is not recommended since these agents lose ...
Ephedrine is a non-catecholamine sympathomimetic with cardiovascular effects similar to those of adrenaline/epinephrine: increased blood pressure, heart rate, and contractility. Like pseudoephedrine it is a bronchodilator, with pseudoephedrine having considerably less effect. [19] [20]
On July 13, the FDA did approve the progestin-only Opill brand for over-the-counter use, which is a step in the right direction. The post Free the Meds: 5 Drugs You Should Be Able To Buy Over the ...
Like many other over-the-counter ingredients, phenylephrine was essentially grandfathered into approval during a sweeping FDA review begun in 1972. It has been sold in various forms for more than ...
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
Levmetamfetamine is excreted in urine 40.8 to 49.0% as unchanged levmetamfetamine and 2.1 to 3.3% as levoamphetamine. [2] [4] [3] The mean elimination half-life of levmetamfetamine ranges between 10.2 and 15.0 hours. [2] [4] For comparison, the elimination half-life of dextromethamphetamine was around 10.2 to 10.7 hours in the same studies.
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