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  2. Nicotine patch - Wikipedia

    en.wikipedia.org/wiki/Nicotine_patch

    A nicotine patch is a transdermal patch that releases nicotine into the body through the skin. It is used in nicotine replacement therapy (NRT), a process for smoking cessation . Endorsed and approved by the U.S. Food and Drug Administration (FDA), it is considered one of the safer NRTs available for the treatment of tobacco use disorder .

  3. Precordial catch syndrome - Wikipedia

    en.wikipedia.org/wiki/Precordial_catch_syndrome

    The underlying cause is unclear. Some believe the pain may be from the chest wall or irritation of an intercostal nerve. [1] [2] Risk factors include psychological stress. [2] The pain is not due to the heart. Diagnosis is based on the symptoms. Other conditions that may produce similar symptoms include angina, pericarditis, pleurisy, and chest ...

  4. Nicotine replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Nicotine_replacement_therapy

    However, the likelihood that someone will stick to a certain treatment varies, with compliance being the highest with nicotine patches, followed by nicotine gum, inhalers, and nasal sprays. [17] Using a few different nicotine replacement methods in combination may improve success rates in stopping tobacco use.

  5. Transdermal patch - Wikipedia

    en.wikipedia.org/wiki/Transdermal_patch

    The microneedle patch (MNPs) is a type of transdermal patch which retains the advantages, but reduces the disadvantages of basic transdermal patches. Embedding as many as 102-104 needles per square centimetre of patch, encapsulated or coated with intended drug, MNPs can easily pass skin tissue known as the stratum corneum which is roughly 20 ...

  6. Nicotine - Wikipedia

    en.wikipedia.org/wiki/Nicotine

    A 2018 Cochrane review found that, in rare cases, nicotine replacement therapy can cause non-ischemic chest pain (i.e., chest pain that is unrelated to a heart attack) and heart palpitations, but does not increase the incidence of serious cardiac adverse events (i.e., myocardial infarction, stroke, and cardiac death) relative to controls. [47]

  7. Nicotine poisoning - Wikipedia

    en.wikipedia.org/wiki/Nicotine_poisoning

    The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...

  8. Smoking cessation - Wikipedia

    en.wikipedia.org/wiki/Smoking_cessation

    Nicotine replacement therapy (NRT): Five medications have been approved by the U.S. Food and Drug Administration (FDA) to deliver nicotine in a form that does not involve the risks of smoking: transdermal nicotine patches, nicotine gum, nicotine lozenges, nicotine inhalers, nicotine oral sprays, and nicotine nasal sprays. [35]

  9. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    It remains unknown if surgery is superior to optimal medical therapy. The STICH trial (Surgical Treatment for IschemiC Heart Failure) will examine the role of medical treatment, coronary artery bypass surgery and left ventricle remodeling surgery in heart failure patients. Results are expected to be published in 2009 [needs update] and 2011. [56]

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