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Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, delirium, agitation, acute psychosis, and hallucinations from alcohol withdrawal. [9][10][11] It may be used by mouth or injection into a muscle or a vein. [9] Haloperidol typically works within 30 to 60 minutes. [9]
The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, and tardive akathisia.
It was used in humans during the 1950s as an antipsychotic,[4]but is now almost exclusively used on animalsas a sedativeand antiemetic. A closely related analogue, chlorpromazine, is still used in humans. The standard pharmaceutical preparation, acepromazine maleate, is used in veterinary medicinein dogs and cats.
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. [ 1 ]
Haloperidol decanoate, sold under the brand name Haldol Decanoate among others, is a typical antipsychotic which is used in the treatment of schizophrenia. [2] [3] [4
In 1948, Swiss pharmacologist Peter N. Witt started his research on the effect of drugs on spiders.The initial motivation for the study was a request from his colleague, zoologist H. M. Peters, to shift the time when garden spiders build their webs from between 2:00 a.m. and 5:00 a.m., which was decidedly inconvenient for Peters, to earlier hours. [4]
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and in pain management. [19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. [20]
Hemangiosarcoma. Hemangiosarcoma is a rapidly growing, highly invasive variety of cancer that occurs almost exclusively in dogs, and only rarely in cats, horses, mice, [1] or humans (vinyl chloride toxicity). It is a sarcoma arising from the lining of blood vessels; that is, blood-filled channels and spaces are commonly observed microscopically.