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Chondroitin sulfate; Dermatan sulfate; Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis. [2] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine ...
Chondroitin, without the "sulfate", has been used to describe a fraction with little or no sulfation. [26] However, this distinction is not used by all. Although the name "chondroitin sulfate" suggests a salt with a sulfate counter-anion , this is not the case, as sulfate is covalently bonded to the sugar.
In 2007, Reichenbach et al. [42] [43] used explicit methods to conduct and report [44] a systematic review of 20 trials and concluded "large-scale, methodologically sound trials indicate that the symptomatic benefit of chondroitin is minimal or nonexistent. Use of chondroitin in routine clinical practice should therefore be discouraged."
Supplements like glucosamine, chondroitin, SAMe, and fish oil might also help. ... Use proper form and appropriate equipment when engaging in certain types of activities, such as sports or lifting ...
The two main proteoglycans that are used in this process are heparan sulfate proteoglycans (HSPGs) and chondroitin sulfate proteoglycans (CSPGs) which are present at high levels in the chondrocyte extracellular matrix and are crucial in regulating chondrocyte maturation. When the GAG chain functions properly, it controls the maturation speed of ...
Dermatan sulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs.. It is also referred to as chondroitin sulfate B, [1] although it is no longer classified as a form of chondroitin sulfate by most sources.
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