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6 Merge with systemic scleroderma. 1 comment. 7 Is the cause known or unknown? 1 comment. 8 Vitamin connections. 1 comment. 9 Overlap with systemic sclerosis ...
Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Genetics of scleroderma: update on single nucleotide polymorphism analysis and microarrays. Curr Opin Rheumatol. 2005 Nov;17(6):761-7. Review. PMID 16224255. I suggest you talk to your doctor. Nephron T|C 08:34, 28 October 2006 (UTC) Having a member of the family with scleroderma increases the rate to 1.3% from a few in a million.
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...
Morphea is a form of scleroderma that is more common in women than men, in a ratio 3:1. [17] Morphea occurs in childhood as well as in adult life. [ 3 ] Morphea is an uncommon condition that is thought to affect 2 to 4 in 100,000 people. [ 18 ]
In reaction to the lack of awareness of the disease in the medical community, she went on to found the Scleroderma Research Foundation in 1987, [2] an organization dedicated to finding a cure. [4] According to the New York Times, "Ms. Monsky's activities generated more than $14 million for research and helped expand understanding of the disease ...
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Anti-Scl-70 (also called anti-topoisomerase I after the type I topoisomerase target [1]) is an anti-topoisomerase antibody-type of anti-nuclear autoantibodies, seen mainly in diffuse systemic scleroderma (with a sensitivity of 28–70%), but is also seen in 10–18% of cases of the more limited form of systemic scleroderma called CREST syndrome. [2]