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  2. Progestogen (medication) - Wikipedia

    en.wikipedia.org/wiki/Progestogen_(medication)

    Certain progestogens are used to support pregnancy, including progesterone, hydroxyprogesterone caproate, dydrogesterone, and allylestrenol. They are used questionably for treatment of recurrent pregnancy loss and for prevention of preterm birth in pregnant women with a history of at least one spontaneous preterm birth. [42]

  3. Progesterone receptor - Wikipedia

    en.wikipedia.org/wiki/Progesterone_receptor

    The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone . In humans, PR is encoded by a single PGR gene residing on chromosome 11q 22, [ 5 ] [ 6 ] [ 7 ] it has two isoforms, PR-A and PR-B , that differ in their ...

  4. Selective progesterone receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Selective_progesterone...

    A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor (PR), the biological target of progestogens like progesterone.A characteristic that distinguishes such substances from full receptor agonists (e.g., progesterone, progestins) and full antagonists (e.g., aglepristone) is that their action differs in different tissues, i.e. agonist in some ...

  5. Antiprogestogen - Wikipedia

    en.wikipedia.org/wiki/Antiprogestogen

    These drugs competitively inhibit progestin at progesterone receptors, acting by blocking the progesterone receptor (PR) and/or inhibiting or suppressing progestogen production. Antiprogestogens are one of three types of sex hormone antagonists , alongside antiestrogens and antiandrogens .

  6. Medroxyprogesterone acetate - Wikipedia

    en.wikipedia.org/wiki/Medroxyprogesterone_acetate

    Progesterone, via transformation into neurosteroids such as 5α-dihydroprogesterone, 5β-dihydroprogesterone, allopregnanolone, and pregnanolone (catalyzed by the enzymes 5α-and 5β-reductase and 3α- and 3β-HSD), is a positive allosteric modulator of the GABA A receptor, and is associated with a variety of effects mediated by this property ...

  7. Etonogestrel - Wikipedia

    en.wikipedia.org/wiki/Etonogestrel

    Etonogestrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. [16] It works by stopping ovulation , thickening the mucus around the opening of the cervix , and altering the lining of the uterus . [ 17 ]

  8. Progesterone (medication) - Wikipedia

    en.wikipedia.org/wiki/Progesterone_(medication)

    Progesterone (P4), sold under the brand name Prometrium among others, is a medication and naturally occurring steroid hormone. [20] It is a progestogen and is used in combination with estrogens mainly in hormone therapy for menopausal symptoms and low sex hormone levels in women.

  9. Segesterone acetate - Wikipedia

    en.wikipedia.org/wiki/Segesterone_acetate

    SGA is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. [1] [3] [9] [10] It has some affinity for the glucocorticoid receptor and has no other important hormonal activity. [1] [3] [9] [10]