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One of the most important factors used to determine the clinical suspicion of malignancy of an adnexal mass is the sonographic appearance of the mass. [2] Indications that the mass is at a higher risk of being malignant include the presence of loculations, nodules, papillary structures, septations, or a size greater than 10 cm. [3] [4]
The QCancer (Ovary) algorithm is used to predict likelihood of ovarian cancer from risk factors. [31] Ovarian-Adnexal Reporting and Data System (ORADS) is a standardized system developed by the American College of Radiology to improve the management and diagnosis of ovarian and adnexal masses. It provides a consistent framework for interpreting ...
Risk factors include ovarian cysts, ovarian enlargement, ovarian tumors, pregnancy, fertility treatment, and prior tubal ligation. [3] [2] [5] The diagnosis may be supported by an ultrasound done via the vagina or CT scan, but these do not completely rule out the diagnosis. [2] Surgery is the most accurate method of diagnosis. [2]
Risk factors for ectopic pregnancy include pelvic inflammatory disease, often due to chlamydia infection; ... an adnexal mass, or adnexal tenderness. [1] ...
The exact pathogenesis of OGCTs is still unknown however, various genetic mutations and environmental factors have been identified. [1] OGCTs are commonly found during pregnancy when an adnexal mass is found during a pelvic examination, ultrasound scans show a solid mass in ovary or blood serum test shows elevated alpha-fetoprotein levels. [1]
A mutation in BRCA1 or BRCA2 can confer a lifetime ovarian cancer risk of 40-50% and 10-20% respectively, [15] with BRCA2 mutations strongly associated with better clinical outcomes. A specific tumour protein 53 ( TP53 ) expression pattern in the Fallopian tube epithelium – the ‘p53 signature’ - is thought to be a precursor marker of HGSC.
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63% of ectopic pregnancies present with an adnexal mass. Depending on the size of the mass, it could be a medical emergency. Depending on the size of the mass, it could be a medical emergency. The term "adnexectomy" in gynaecology is often used for salpingo - oophorectomy (removal of both: fallopian tubes and ovaries).