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  2. Platelet storage pool deficiency - Wikipedia

    en.wikipedia.org/wiki/Platelet_storage_pool...

    Platelet storage pool deficiency is a family of clotting disorders characterized by deficient granules in platelets.Individuals with these disorders have too few or abnormally functioning alpha granules, delta granules, or both alpha and delta granules and are therefore unable to form effective clots, which leads to prolonged bleeding.

  3. von Willebrand disease - Wikipedia

    en.wikipedia.org/wiki/Von_Willebrand_disease

    Von Willebrand disease (VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [ 1 ] It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion .

  4. Vonicog alfa - Wikipedia

    en.wikipedia.org/wiki/Vonicog_alfa

    Vonicog alfa, sold under the brand names Vonvendi and Veyvondi, is a medication used to control bleeding in adults with von Willebrand disease (an inherited bleeding disorder). [6] [5] [7] [8] It is a recombinant von Willebrand factor. [6] [5] The most common adverse reactions are generalized itching, vomiting, nausea, dizziness, and vertigo. [6]

  5. FDA Approves Takeda's Vonvendi As Prophylactic Treatment In ...

    www.aol.com/news/fda-approves-takedas-vonvendi...

    The FDA has approved Takeda Pharmaceutical Co Ltd's (NYSE: TAK) Vonvendi [von Willebrand factor (Recombinant)] for routine prophylaxis to reduce the frequency of bleeding episodes in Type 3 von ...

  6. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Chronic kidney failure, liver disease, haematological malignancy, recent or current chemotherapy, advanced heart failure, mild forms of inherited bleeding disorders (e.g. haemophilia, Von Willebrand's disease) and idiopathic thrombocytopenic purpura.

  7. A vet’s guide to Von Willebrand Disease in dogs - AOL

    www.aol.com/vet-guide-von-willebrand-disease...

    Type 1 von Willebrand Disease in dogs. Type 1 von Willebrand Disease is the most common type, and also the mildest. It occurs when dogs have a mild deficiency in all the proteins making up their ...

  8. Ristocetin-induced platelet aggregation - Wikipedia

    en.wikipedia.org/wiki/Ristocetin-induced...

    It is similar to the ristocetin cofactor assay but has the added benefit in that it helps in the diagnosis of type 2B/pseudo von Willebrand disease (vWD) and Bernard–Soulier syndrome because it uses patient's live endogenous platelets, whereas ristocetin cofactor assay tests the function of only the vWF and not the platelets. Ristocetin ...

  9. Weibel–Palade body - Wikipedia

    en.wikipedia.org/wiki/Weibel–Palade_body

    Weibel–Palade bodies are the storage granules of endothelial cells, the cells that form the inner lining of the blood vessels and heart. [1] They manufacture, store and release two principal molecules, von Willebrand factor and P-selectin, and thus play a dual role in hemostasis and inflammation.

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