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  2. Atipamezole - Wikipedia

    en.wikipedia.org/wiki/Atipamezole

    The minimum lethal dose in dogs is over 5 mg/m 2; dogs have tolerated getting ten times the standard dose. [9] [33] Signs of overdose include panting, trembling, vomiting, and diarrhea, as well as increased blood levels of creatine kinase, aspartate transaminase, and alanine transaminase. Dogs who received atipamezole without first receiving ...

  3. Yohimbine - Wikipedia

    en.wikipedia.org/wiki/Yohimbine

    Yohimbine (/ j oʊ ˈ h ɪ m b iː n /), [2] also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia johimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco. Yohimbine is an α 2-adrenergic receptor antagonist, and has been used in a variety of research ...

  4. Rauwolscine - Wikipedia

    en.wikipedia.org/wiki/Rauwolscine

    Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauvolfia and Corynanthe (including Pausinystalia). [1] It is a stereoisomer of yohimbine. [1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac. [1]

  5. Indole alkaloid - Wikipedia

    en.wikipedia.org/wiki/Indole_alkaloid

    [55] [56] Yohimbine is more selective to α 2 adrenoceptor; [56] by blocking presynaptic α 2-adrenoceptors, it increases the release of norepinephrine thereby raising the blood pressure. Yohimbine was used for the treatment of erectile dysfunction in men until emergence of more efficient drugs. [57] Some alkaloids affect the turnover of ...

  6. If you’re finding your teenage dog difficult, here’s what an ...

    www.aol.com/finding-teenage-dog-difficult-award...

    If your teenage dog is showing more signs of reactivity, meanwhile, you might find this article useful: My reactive dog impacted my entire household, here's what I did about it. Show comments ...

  7. Medetomidine - Wikipedia

    en.wikipedia.org/wiki/Medetomidine

    Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.

  8. Seattle City Council’s first act of 2025? Filling its ... - AOL

    www.aol.com/news/seattle-city-council-first-act...

    (The Center Square) – The Seattle City Council’s first action of the new year will be finding a replacement for the District 2 position. Earlier this month, Tammy Morales announced that she ...

  9. Paid biweekly? Here's when you could get an 'extra' paycheck ...

    www.aol.com/paid-biweekly-heres-could-extra...

    People looking to save money for a big trip or financial investment may want to make plans around an "extra" paycheck in their pocket.. Employees who get paid on a biweekly basis (every other week ...