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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
Often reserved for spastic cerebral palsy, baclofen can be administered through an intrathecal pump implanted just below the skin of the abdomen or behind the chest wall, with a catheter connected directly to the base of the spine. Intrathecal baclofen pumps sometimes carry serious clinical risks, such as infection or a possibly fatal sudden ...
Also external pumps, with or without a subcutaneous port are used for intrathecal delivery. The implantable medical device requires a surgical procedure; sometimes a surgeon performs a trial intrathecal injection or implants a temporary intrathecal catheter and pump to determine if the medication works to begin with, and thus if a pump is ...
Some medications may be used to treat persistent hiccups, per the Mayo Clinic, such as baclofen, chlorpromazine and metoclopramide. In severe cases, nerve blocks or surgical procedures may be ...
Baclofen in my view was probably just suppressing alcohol withdrawal symptoms. Baclofen's suppression of temporary withdrawal symptoms may be being misinterpreted as being a successful treatment of alcoholism. We need to be careful about adding primary sources, especially weak primary sources and giving undue weight.
A baclofen pump has been used to treat patients of all ages exhibiting muscle spasticity along with dystonia. The pump delivers baclofen via a catheter to the thecal space surrounding the spinal cord. The pump itself is placed in the abdomen. It can be refilled periodically by access through the skin. Baclofen can also be taken in tablet form [40]
The pump can be adjusted if muscle tone is worse at certain times of the day or night. The baclofen pump is most appropriate for individuals with chronic, severe stiffness or uncontrolled muscle movement throughout the body. [80] There is a small amount of evidence that baclofen pumps are effective in the short term. [69]
The intrathecal solution is a liquid injected into the spinal fluid for trial, and if successful in reducing spasticity, thereafter administered via an intrathecal pump, which has variously been proven potentially very dangerous on one or another level with long-term use (see article), including sudden and potentially lethal baclofen overdose ...
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related to: baclofen pump forums and reviews- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
Ranked at No. 20 on the 2020 Disruptor 50 list. - CNBC