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  2. Median lethal dose - Wikipedia

    en.wikipedia.org/wiki/Median_lethal_dose

    In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. [1] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.

  3. Lethal dose - Wikipedia

    en.wikipedia.org/wiki/Lethal_dose

    In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. Because resistance varies from one individual to another, the "lethal dose" represents a dose (usually recorded as dose per kilogram of subject body weight) at which a given percentage of subjects will die.

  4. Fixed-dose procedure - Wikipedia

    en.wikipedia.org/wiki/Fixed-dose_procedure

    The fixed-dose procedure (FDP), proposed in 1992 by the British Toxicology Society, is a method to assess a substance's acute oral toxicity. [1] [2]In comparison to the older LD 50 test developed in 1927, this procedure produces similar results while using fewer animals and causing less pain and suffering. [3]

  5. Potassium cyanide - Wikipedia

    en.wikipedia.org/wiki/Potassium_cyanide

    The expected LD100 dose (human) for potassium cyanide is 200–300 mg while the median lethal dose LD50 is estimated at 140 mg. [16] People who killed themselves, were killed, or killed someone else using potassium cyanide include: Viktor Meyer, 19th-century German chemist, died by suicide in 1897 after taking cyanide [17]

  6. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]

  7. Backpacks full of $1.1 million worth of cocaine found near ...

    www.aol.com/news/backpacks-full-1-1-million...

    Agents on patrol discovered two backpacks stuffed with more than $1.1 million worth of cocaine in Washington state near the border with Canada, U.S. Customs and Border Protection said Monday. The ...

  8. Adorable Goldendoodle Goes All Out to Stop Dad From Reading ...

    www.aol.com/adorable-goldendoodle-goes-stop-dad...

    If you don't have the energy to walk them after a long day, you can feel confident that they get their daily dose of exercise in. They may even come home and take an extra long nap!

  9. It's the end of the road for these cars: Models that won't ...

    www.aol.com/end-road-cars-models-wont-131806139.html

    A number of car models won't ring in the new year.. The Ford Edge, Toyota Venza and Mini Clubman are just some of the vehicles that won't make it past model year 2024 in U.S. markets.