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Some authors consider that early pronounced contrast enhancement of a nodule within 1–2 cm developed on a cirrhotic liver is sufficient for HCC diagnosis. These results prove that for a correct characterization of the lesions it is necessary to extend the examination time to 5 minutes or even longer. [citation needed] Fig. 11.
Other scans include CT of the abdomen and MRI. [45] A CT scan is non-invasive and may be helpful in the diagnosis. [45] Compared to the ultrasound, CT scans tend to be more expensive. MRI provides excellent evaluation; however, is a high expense. [45] Liver cirrhosis on CT imaging of the abdomen in transverse view
Hepatic hydrothorax is a rare form of pleural effusion that occurs in people with liver cirrhosis. It is defined as an effusion of over 500 mL in people with liver cirrhosis that is not caused by heart, lung, or pleural disease. It is found in 5–10% of people with liver cirrhosis and 2–3% of people with pleural effusions.
CT appearance of liver in congestive hepatopathy, sometimes referred to as a nutmeg liver. Due to congestion, contrast does not flow through the liver in a normal manner. Axial and coronal images in the portal venous phase.
FibroTest, known as FibroSure in the US, is a biomarker test that uses the results of six blood serum tests to generate a score that is correlated with the degree of liver damage in people with a variety of liver diseases. FibroTest has the same prognostic value as a liver biopsy.
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Biopsy results show significant variability (up to 40% for fibrosis diagnosis) which can lead to a wrong diagnosis. The result depends on the representativity of the punctured sample. [4] Only 5% of patients at risk of fibrosis have liver biopsy.
In terms of HCC diagnosis, it is recommended that people with risk factors (including known chronic liver disease, cirrhosis, etc.) should receive screening ultrasounds. If the ultrasound shows a focal area that is larger than 1 centimeter in size, patients should then get a triple-phase contrast-enhanced CT or MRI scan. [17]