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Peak symptoms: The rash usually reaches its peak intensity within 3–4 days after onset. [1] [4] Associated symptoms, such as itching, burning sensation, and mild swelling are often most pronounced during this stage. [3] Resolution phase: In most cases, the rash and associated symptoms begin to subside after 3–4 days without specific treatment.
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1]
A computertomographie of a 13-year-old child who was diaognised by "Trevor disease", which is an additional bone growth on the knee or ankle. Ankle problems occur frequently, having symptoms of pain or discomfort in the ankles. [1] [2] Mild ankle pain can often be cured by home treatments, although these may be slow to take effect.
Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan, a precursor for the vitamin. Low plasma tryptophan is a non-specific indicator, meaning it can have other causes. The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24]
A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]
Niacin has been linked to a higher risk of heart disease. It is often added to flour and fortified cereals in the U.S. The B vitamin used to be a popular medication to lower high cholesterol.
The primary treatment for megavitamin-B 6 syndrome is to stop taking supplemental vitamin B 6. [14] Physical therapy, including vestibular rehabilitation, has been used in attempts to improve recovery following cessation of vitamin B 6 supplementation. [50] [11] Medications such as amitriptyline have been used to help with neuropathic pain. [19]
You eat niacin in foods like chicken breast, marinara sauce, salmon, and brown rice, and consuming it helps your body convert the food you eat into energy, she says. But benefits abound when you ...
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