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Tea tree oil is defined by the International Standard ISO 4730 ("Oil of Melaleuca, terpinen-4-ol type"), containing terpinen-4-ol, γ-terpinene, and α-terpinene as about 70% to 90% of whole oil, while p-cymene, terpinolene, α-terpineol, and α-pinene collectively account for some 15% of the oil (table).
The top 25 pharmacy chain stores represent about 38,000 pharmacy locations in the U.S. and employ about 149,000 on-staff pharmacists. California has 8,015 pharmacies, the most of any state. Texas, Florida, New York, and Pennsylvania round out the top five states for pharmacy locations. [1]
A primary constituent of tea tree oil, [1] it is obtained as an extract from the leaves, branches, and bark of Melaleuca alternifolia Cheel. [2] [3] [4] Despite considerable basic and preliminary clinical research of terpinen-4-ol and tea tree oil, its biological properties and potential for clinical uses have not been established as of 2019. [2]
One Walgreens pharmacy in Fort Myers, Florida, ordered 95,800 pills in 2009, but by 2011, this number had jumped to 2.2 million pills in one year. Another example was a Walgreens pharmacy in Hudson, Florida, a town of 34,000 people near Clearwater, that purchased 2.2 million pills in 2011, the DEA said.
"Many recipes exist, but one that is repeated often is to add one to two drops of tea tree oil in 12 drops of carrier oil," says Dr. Camp. (Go for neutral options such as almond oil or coconut oil.)
Melaleuca alternifolia is notable for its essential oil, which has antifungal and antibiotic properties in vitro. [30] [31] Though it is safe for topical applications, [32] tea tree oil is toxic if ingested orally. [30] The oil is produced on a commercial scale and marketed as tea tree oil. [33]
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