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Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1, the first identified strain of the SARS-related coronavirus. [3] The first known cases occurred in November 2002, and the syndrome caused the 2002–2004 SARS outbreak .
Scanning electron micrograph of SARS virions. Severe acute respiratory syndrome (SARS) is the disease caused by SARS-CoV-1. It causes an often severe illness and is marked initially by systemic symptoms of muscle pain, headache, and fever, followed in 2–14 days by the onset of respiratory symptoms, [13] mainly cough, dyspnea, and pneumonia.
The SARS-related coronavirus was one of several viruses identified by the World Health Organization (WHO) in 2016 as a likely cause of a future epidemic in a new plan developed after the Ebola epidemic for urgent research and development before and during an epidemic towards diagnostic tests, vaccines and medicines.
Cholera (caused by Vibrio cholerae bacteria) and bubonic plague, or the Black Death (caused by the bacterium Yersinia pestis) are some of the most famous examples of how devastating a pandemic can be.
Coronaviruses can cause pneumonia (either direct viral pneumonia or secondary bacterial pneumonia) and bronchitis (either direct viral bronchitis or secondary bacterial bronchitis). [92] The human coronavirus discovered in 2003, SARS-CoV , which causes severe acute respiratory syndrome (SARS), has a unique pathogenesis because it causes both ...
Not all select agents require BSL-4 handling, namely select bacteria and toxins, but most select agent viruses do (with the notable exception of SARS-CoV-1 which can be handled in BSL3). Many non-select agent viruses are often handled in BSL-4 according to facility SOPs or when dealing with new viruses closely related to viruses that require BSL-4.
“They work well at inactivating influenza and SARS-CoV-2 [the virus that causes COVID-19].” ... “But they work less well against certain bacteria and other pathogens.” ... This is the most ...
SARS‑CoV‑2 is a strain of the species Betacoronavirus pandemicum (SARSr-CoV), as is SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak. [ 2 ] [ 17 ] There are animal-borne coronavirus strains more closely related to SARS-CoV-2, the most closely known relative being the BANAL-52 bat coronavirus.