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  2. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]

  3. Peripheral artery disease - Wikipedia

    en.wikipedia.org/wiki/Peripheral_artery_disease

    The illustration shows how PAD can affect arteries in the legs. Figure A shows a normal artery with normal blood flow. The inset image shows a cross-section of the normal artery. Figure B shows an artery with plaque buildup that is partially blocking blood flow. The inset image shows a cross-section of the narrowed artery.

  4. Daily low-dose aspirin has its benefits — and risks. Here's ...

    www.aol.com/lifestyle/aspirin-every-day-why-not...

    Aspirin helps prevent blood clots from forming, which is the leading cause of heart attack and stroke, but the drug also carries a risk of bleeding. That risk can outweigh aspirin’s benefits in ...

  5. Vascular disease - Wikipedia

    en.wikipedia.org/wiki/Vascular_disease

    Peripheral artery disease – occurs when atheromatous plaques build up in the arteries that supply blood to the arms and legs, causing the arteries to narrow or become blocked. [ 1 ] Erythromelalgia - a rare peripheral vascular disease with symptoms that include burning pain, increased temperature, erythema and swelling that generally affect ...

  6. Many Older Adults Take Daily Aspirin to Cut Cardiovascular ...

    www.aol.com/lifestyle/many-older-adults-daily...

    Many Americans 60 years and older still take daily aspirin to help prevent cardiovascular disease, even though it can pose significant health risks. ... Aspirin is a blood-thinner, meaning that it ...

  7. A change of heart? Why daily aspirin might not be ... - AOL

    www.aol.com/news/change-heart-why-daily-aspirin...

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  8. Thrombosis - Wikipedia

    en.wikipedia.org/wiki/Thrombosis

    It most commonly affects leg veins, such as the femoral vein. Three factors are important in the formation of a blood clot within a deep vein—these are: the rate of blood flow, the thickness of the blood and; qualities of the vessel wall. Classical signs of DVT include swelling, pain and redness of the affected area. [3]

  9. If you take aspirin daily, you could raise your risk of this ...

    www.aol.com/lifestyle/aspirin-daily-could-raise...

    More than 40% of adults aged 60 and over take the pill to lower the risk of blood clots, but it’s a recommendation that many doctors have cut back on making recently.