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The antibiotic, which would be the first new gonorrhea treatment approved in decades, could make it to market by 2025. The World Health Organization estimates that globally there are more than 82 ...
Zoliflodacin (development codes AZD0914 and ETX0914) is an experimental antibiotic that is being studied for the treatment of infection with Neisseria gonorrhoeae (). [1] It has a novel mechanism of action which involves inhibition of bacterial type II topoisomerases. [2]
The WHO's program for monitoring trends in drug-resistant gonorrhea found in a study that from 2009 to 2014 there was widespread resistance to the first-line medicine ciprofloxacin, increasing ...
Gonorrhea can be prevented with the use of condoms, having sex with only one person who is uninfected, and by not having sex. [1] [3] Treatment is usually with ceftriaxone by injection and azithromycin by mouth. [4] [5] Resistance has developed to many previously used antibiotics and higher doses of ceftriaxone are occasionally required.
Each drug should be administered as a single dose, with the gentamicin entering intramuscularly at a concentration of 240 mg, along with 2 g of azithromycin taken orally. [79] If an individual is not allergic to cephalosporins but ceftriaxone is unavailable, an alternative treatment is a single dose of 800 mg cefixime consumed orally. [79]
A study out of the University of York shows that carbon monoxide-releasing molecules could be the key to developing a new antibiotic to treat gonorrhea.
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