Search results
Results from the WOW.Com Content Network
Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity.
Variants of the MTCH2 gene may be associated with obesity. [10] MTCH2 represses mitochondrial metabolism such that a deficiency of MTCH2 increases energy consumption and production by mitochondria. [ 9 ]
16p11.2 deletion syndrome is a rare genetic condition caused by microdeletion on the short arm of chromosome 16. Most affected individuals experience global developmental delay and intellectual disability, as well as childhood-onset obesity. [1] 16p11.2 deletion is estimated to account for approximately 1% of autism spectrum disorder cases. [3] [4]
Obesity risk factors can be genetic or environmental — the latter has to do with lifestyle choices and things you don’t have as much control over, like illness or work stress.
Monogenic obesity is excess weight caused by a mutation in a single gene, as opposed to syndromic obesity not tied to a single gene variation and most obesity, which is caused by multiple genetic and environmental risk factors. Monogenetic obesity mostly affects the hypothalamus and leptin–melanocortin system (see hypothalamic obesity ...
Syndromic obesity (SO) refers to obesity when it occurs as part of a syndrome, often along with intellectual disability. Often syndromic obesity is mediated by abnormal development of the hypothalamus (see hypothalamic obesity). Known types of syndromic obesity include some types of monogenic obesity and: [1] [2] Prader Willi syndrome; Bardet ...
The obesity rate among U.S. adults fell in 2023 for the first time in over a decade, according to a new study released on Friday. The study published in the journal JAMA Health Forum found that ...
Research has found that variations in the AR gene on the X chromosome, which instructs the body about how to create androgen receptors, may contribute to androgenetic alopecia.