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Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.
N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam. It is a colorless liquid, although impure samples can appear yellow. It is miscible with water and with most common organic solvents. It also belongs to the class of dipolar aprotic solvents such as dimethylformamide and dimethyl sulfoxide.
As a generic and under the brand name Celexa, citalopram is prescribed off-label to treat anxiety disorders, including social anxiety disorder, panic disorder and generalized anxiety disorder.
According to the Anxiety and Depression Association of America (ADAA), 6.8 million adults have GAD. Other anxiety disorders include obsessive-compulsive disorder, panic disorder, post-traumatic ...
Side effects of pyrovalerone include decreased appetite, anxiety, fragmented sleep or insomnia, and trembling, shaking, or muscle tremors. Withdrawal symptoms following abuse upon discontinuation often results in depression. The R-enantiomer of pyrovalerone is devoid of pharmacologic activity. [5]
Amisulpride is approved and used at low doses in the treatment of dysthymia and major depressive disorder. [10] [20] [11] [21] [22] [23] Whereas typical doses used in schizophrenia block postsynaptic dopamine D 2-like receptors and reduce dopaminergic neurotransmission, low doses of amisulpride preferentially block presynaptic dopamine D 2 and D 3 autoreceptors and thereby disinhibit dopamine ...
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Soclenicant, also known by its developmental code names BNC210 and IW-2143, is an anxiolytic drug that acts via negative allosteric modulation of the α 7-nicotinic acetylcholine receptor, [1] by Bionomics Limited. It is currently being investigated for the treatment of post traumatic stress disorder. [2]