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Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [3] Effectiveness appears similar to baclofen or diazepam. [4] It is taken by mouth. [5]
Tizanidine is perhaps the most thoroughly studied clonidine analog, and is an agonist at α 2-adrenergic receptors, but reduces spasticity at doses that result in significantly less hypotension than clonidine. [26]
Cyclobenzaprine, sold under several brand names including, historically, Flexeril, is a muscle relaxer used for muscle spasms from musculoskeletal conditions of sudden onset. [5] It is not useful in cerebral palsy. [5] It is taken by mouth. [5] Common side effects include headache, feeling tired, dizziness, and dry mouth. [5]
"We're suckers for quick fixes," Emily Feivor, a registered dietician, tells PEOPLE about the claim that honey, lemon, water, and ginger can help you lose weight
The results reported in this study show that the previously described facilitatory actions of NA on these neurons are reproduced by ionophoretic application of the alpha 1-receptor agonist phenylephrine and, although to a lesser degree, by the beta -receptor agonist isoproterenol, but not by the alpha 2-receptor agonists clonidine and tizanidine.
We found the best technology for adults over 65 at CES this year. From AI aids to ‘aging in place’ smart home solutions, the annual tech show kept older users in mind.
Eli Lilly’s weight loss drug Zepbound is no longer in short supply, the FDA said, worrying patients who use cheaper, off-brand versions of the drug. On Thursday, Dec. 19, the U.S. Food and Drug ...
Learn how to download and install or uninstall the Desktop Gold software and if your computer meets the system requirements.