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  2. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    "There are certain substances in grapefruit juice and grapefruit that may affect the way the body handles a medication," says Leonard. "This can result in fluctuating levels of a medication in the ...

  3. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Grapefruit juice may potentially reduce the effectiveness of tamoxifen. [84] Trazodone (Desyrel): Little or no interaction with grapefruit juice. [85] Verapamil (Calan SR, Covera HS, Isoptin SR, Verelan): atrioventricular conduction disorders. [61] Warfarin (coumadin) [86] Zolpidem (Ambien): Little or no interaction with grapefruit juice [85]

  4. Grapefruit juice - Wikipedia

    en.wikipedia.org/wiki/Grapefruit_juice

    Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]

  5. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors , directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors , and their simultaneous consumption results in the overstimulation of the receptor, which can ...

  6. What You Need To Know Before Eating Your Daily Grapefruit - AOL

    www.aol.com/know-eating-daily-grapefruit...

    The Health Benefits Of Grapefruit. Water-rich grapefruit contains a variety of nutrients that your body needs. One cup of grapefruit contains over 100% of your daily vitamin C, in addition to ...

  7. Can I Have Grapefruit with Cialis? - AOL

    www.aol.com/grapefruit-cialis-115700221.html

    Unlike orange juice, grapefruit juice can impact how Cialis is metabolized in your body, leading to increased levels of the medication in your system. That can be dangerous for a variety of reasons.

  8. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  9. People Claim the 'Grapefruit Diet' Can Help You Lose 10 ... - AOL

    www.aol.com/people-claim-grapefruit-diet-help...

    Photo: Shutterstock. Design: Eat This, Not That!The Grapefruit Diet has been a popular weight-loss trend for decades, promising rapid weight loss of 10+ pounds in just a few weeks. The diet calls ...