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Plato's early dialogues are often called his 'aporetic' (Greek: ἀπορητικός) dialogues, because they typically end in aporia.In such a dialogue, Socrates questions his interlocutor about the nature or definition of a concept, e.g., virtue or courage.
Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. [1] [2] The classic feature of psoriatic arthritis is swelling of entire fingers and toes with a sausage-like appearance ("sausage digit"). [3]
Psoriatic erythroderma can be congenital or secondary to an environmental trigger. [12] [13] [14] Environmental triggers that have been documented include sunburn, skin trauma, psychological stress, systemic illness, alcoholism, drug exposure, chemical exposure (e.g., topical tar, computed tomography contrast material), and the sudden cessation of medication.
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [4] [5] These areas are red, pink, or purple, dry, itchy, and scaly.[8] [3] Psoriasis varies in severity from small localized patches to complete body coverage. [3]
Concurrent use of strong cytochrome P450 enzyme inducers has been shown to decrease exposure of apremilast and can result in reduced or loss of efficacy of apremilast. . Using it simultaneously with strong P450 enzyme inducers, including rifampicin, phenobarbital, carbamazepine, phenytoin, [4] and St. John's wort is not recomm
Spondyloarthritis (SpA), also known as spondyloarthropathy, is a collection of clinical syndromes that are connected by genetic predisposition and clinical manifestations. [1]
People suffering from sacroiliitis can often experience symptoms in a number of different ways, however it is commonly related to the amount of pressure that is put onto the sacroiliac joint.
Ustekinumab is used to treat psoriasis. [29] This includes psoriatic arthritis when it affects the skin. [31] [29] It is indicated for the treatment of adult and adolescent patients (12 years and older) with moderate to severe plaque psoriasis (Ps) who are candidates for phototherapy or systemic therapy, and adults with active psoriatic arthritis (PsA) alone or in combination with methotrexate.