Search results
Results from the WOW.Com Content Network
Non-structural Protein 6 (NSP6) is one of the two non-structural proteins that gene 11 in rotavirus encodes for alongside NSP5. [1] It is a putative transmembrane domain protein. [2] NSP6 is composed of six transmembrane domains and a C terminal tail. [3]
In virology, a nonstructural protein is a protein encoded by a virus but that is not part of the viral particle. [1] They typically include the various enzymes and transcription factors the virus uses to replicate itself, such as a viral protease (3CL/nsp5, etc.), an RNA replicase or other template-directed polymerases, and some means to control the host.
A structural gene is a gene that codes for any RNA or protein product other than a regulatory factor (i.e. regulatory protein).A term derived from the lac operon, structural genes are typically viewed as those containing sequences of DNA corresponding to the amino acids of a protein that will be produced, as long as said protein does not function to regulate gene expression.
RoXaN (Rotavirus 'X'-associated non-structural protein) also known as ZC3H7B (zinc finger CCCH-type containing 7B), is a protein that in humans is encoded by the ZC3H7B gene. [5] RoXaN is a protein that contains tetratricopeptide repeat and leucine-aspartate repeat as well as zinc finger domains.
Nsp12 is a non-structural protein in the Coronavirus genome. Its gene is part of the ORF1ab reading frame and it is part of the pp1ab polyprotein; it is cleaved by 3CL pro. [1] Nsp12 is a multi-domain subunit: it consists of an N-terminal nidovirus-specific extension (NiRAN) domain, an interface domain, and a C-terminal RNA-dependent RNA ...
The gene of interest replaces the viral structural proteins. The RNA polymerase encoded by the non-structural proteins, transcribes the gene of interest from a specific promoter (the subgenomic promoter). This subgenomic mRNA encoding the gene of interest is produced at high levels and is capped by a protein component of the non-structural ...
Viral proteins are grouped according to their functions, and groups of viral proteins include structural proteins, nonstructural proteins, regulatory proteins, and accessory proteins. [1] Viruses are non-living and do not have the means to reproduce on their own, instead depending on their host cell's machinery to do this.
The four non-structural protein genes are encoded in the 5′ two-thirds of the genome, while the three structural proteins are translated from a subgenomic mRNA colinear with the 3′ one-third of the genome. There are two open reading frames (ORFs) in the genome, nonstructural and structural. The first is non-structural and encodes proteins ...