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Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [1] Complications may include seizures, cerebral palsy, or kernicterus. [1] In most of cases there is no specific underlying physiologic disorder. [2]
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]
Physiologic jaundice can be a benign condition that presents in newborns until two weeks of life. [2] However, jaundice that continues after two weeks requires follow up with measurement of total and conjugated bilirubin. [3] Elevated levels of conjugated bilirubin are never benign and require further evaluation for neonatal cholestasis. [3]
Initially, the symptoms of biliary atresia are indistinguishable from those of neonatal jaundice, a usually harmless condition commonly seen in infants.However, infants with biliary atresia develop progressive conjugated jaundice, pale white stools, and dark urine.
Clinically, jaundice or dark urine present in approximately one-third of the cases, and most of the symptoms are related to anemia. [5] Other less commonly observed causes of hemolysis include: Hemolysis secondary to drug toxicity [15] Thalassemia minor [16] Congenital dyserythropoietic anemia [17]
This bizarre side effect of eating too many carrots mostly occurs in children, and it is often misdiagnosed as jaundice, because of the similar symptoms. However, carotenemia doesn’t cause ...
Treatment for neonatal jaundice is significantly cheaper than the cost of lifelong care, doctors say. First launched in Vietnam in 2019, Project Oscar has helped about 150,000 children in the ...
Early symptoms include anemia, jaundice, splenomegaly, and fatigue. [2] Acute cases can threaten to cause hypoxia secondary to anemia and acute kernicterus through high blood levels of bilirubin, particularly in newborns. Most cases can be detected soon after birth. Testing for HS is available for the children of affected adults.