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  2. Timeline of the opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_the_opioid...

    1911 - 1990s According to the FDA's Timeline of Selected FDA Activities and Significant Events Addressing Opioid Misuse and Abuse, before the 1990s, most opioid pain medications were used to manage pain that was either acute or related to cancer. The FDA said that there was an increase in the use of opioids because physicians were not treating ...

  3. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    Opioids are among the world's oldest known drugs. [13] [14] Use of the opium poppy for medical, recreational, and religious purposes can be traced to the 4th century BCE, when Hippocrates wrote about it for its analgesic properties, stating, "Divinum opus est sedare dolores." ("Divine work is the easing of pain") [15]

  4. Opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic

    While the rates of opioid prescriptions increased between 2001 and 2010, the prescription of non-opioid pain relievers (aspirin, ibuprofen, etc.) decreased from 38% to 29% of ambulatory visits in the same time period, [25] and there has been no change in the amount of pain reported in the U.S. [26] This has led to differing medical opinions ...

  5. History of aspirin - Wikipedia

    en.wikipedia.org/wiki/History_of_aspirin

    By the 1970s, aspirin had a relatively small portion of the pain reliever market, and in the 1980s sales decreased even more when ibuprofen became available without prescription. [3]: 212–217 Also in the early 1980s, several studies suggested a link between children's consumption of aspirin and Reye's syndrome, a

  6. Paregoric - Wikipedia

    en.wikipedia.org/wiki/Paregoric

    They were available over-the-counter without a prescription in many states until the early 1990s, at which time the FDA banned the sale of anti-diarrheal drugs containing kaolin and pectin; also, Donnagel-PG contained tincture of belladonna, which became prescription-only on January 1, 1993.

  7. Anacin - Wikipedia

    en.wikipedia.org/wiki/Anacin

    Early Anacin radio commercials appeared in radio shows and dramas of the 1940s and '50s. These "formulaic" commercials usually claimed that Anacin was being actively prescribed by doctors and dentists at the time, treated " headaches , neuritis and neuralgia ", and that it contained "a combination of medically proven ingredients, like a doctor ...

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  9. Secobarbital - Wikipedia

    en.wikipedia.org/wiki/Secobarbital

    Lilly's Seconal came in a bright orange/red bullet shaped capsule known as a Pulvule. Prescription use of secobarbital decreased beginning in the early 1980s by which time benzodiazepines had become increasingly common. Secobarbital has acquired many nicknames, the most common being "reds," "red devils," or "red dillies" (because of the color ...

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