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Both Jarisch and Herxheimer observed reactions in patients with syphilis treated with mercury. The reaction was first seen following treatment in early and later stages of syphilis treated with Salvarsan, mercury, or antibiotics. Jarisch thought that the reaction was caused by a toxin released from the dying spirochetes. [11]
Syphilis can be effectively treated with antibiotics. [4] The preferred antibiotic for most cases is benzathine benzylpenicillin injected into a muscle. [4] In those who have a severe penicillin allergy, doxycycline or tetracycline may be used. [4] In those with neurosyphilis, intravenous benzylpenicillin or ceftriaxone is recommended. [4]
When used to treat syphilis a reaction known as Jarisch-Herxheimer may occur. [2] It is not recommended in those with a history of penicillin allergy or procaine allergy. [1] [2] Use during pregnancy and breastfeeding is relatively safe. [1] [2] Procaine benzylpenicillin is in the penicillin and beta lactam family of medications. [2]
Penicillin is the most commonly used antibiotic to treat syphilis. Other options may be used if you are allergic to penicillin, or your doctor may recommend a regimen that will allow your body to ...
Syphilis is curable with a course of antibiotics. The CDC recommends an injection of long-acting penicillin G benzathine to treat the primary, secondary or early latent stages of syphilis.
The so-called delabeling of penicillin allergies, doctors say, would have major health impacts: faster and more effective treatments for people who have spent their lives avoiding penicillin and ...
Benzylpenicillin, also known as penicillin G (PenG [4]) or BENPEN, [5] is an antibiotic used to treat a number of bacterial infections. [6] This includes pneumonia, strep throat, syphilis, necrotizing enterocolitis, diphtheria, gas gangrene, leptospirosis, cellulitis, and tetanus. [6] It is not a first-line agent for pneumococcal meningitis. [6]
Without treatment, syphilis can spread to the brain, eye or ear, and in some severe cases, cause dementia, blindness or hearing loss. ... one injection of long-acting penicillin can cure the early ...
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