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The USP Controlled Room Temperature is a series of United States Pharmacopeia guidelines for the storage of pharmaceuticals; [1] the relevant omnibus standard is USP 797. [2] [3] Although 100% compliance remains challenging for any given facility, [4] the larger protocol may be regarded as constituting a form of clean room [5] which is included in a suite of best practices.
Temperature settings for refrigerator and freezer compartments are often given arbitrary numbers by manufacturers (for example, 1 through 9, warmest to coldest), but generally 3 to 5 °C (37 to 41 °F) [3] is ideal for the refrigerator compartment and −18 °C (0 °F) for the freezer. Some refrigerators must be within certain external ...
Accurate and uniform temperature in a refrigerator plays a key role in ensuring the life of vaccines, reagents and other biologicals. Research has shown that minor variances in temperature such as those in a household refrigerator can compromise the effectiveness of your biologicals, risking up to thousands of dollars in valuable contents.
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The refrigerator should maintain a temperature between 2° and 8 °C (36° and 46 °F). Freezers should maintain a temperature between -50° and -15 °C (-58° and +5 °F). [14] Thermometers are useful to monitor the temperature by placing at the storage unit's central location, adjacent to the vaccines.
Always refrigerate perishable food within 2 hours—1 hour when the temperature is above 90°F (32.2°C). Check the temperature of your refrigerator and freezer with an appliance thermometer. The refrigerator should be at 40°F (4.4°C) or below and the freezer at 0°F (-17.7°C) or below. [27]
A solar-powered refrigerator is a refrigerator which runs on energy directly provided by sun, and may include photovoltaic or solar thermal energy. Solar-powered refrigerators are able to keep perishable goods such as meat and dairy cool in hot climates and are used to keep much-needed vaccines at their appropriate temperature to avoid spoilage.
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