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  2. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    However, when TSH is measured by itself, it can yield misleading results, so additional thyroid function tests must be compared with the result of this test for accurate diagnosis. [4] [5] [6] TSH is produced in the pituitary gland. The production of TSH is controlled by thyrotropin-releasing hormone (TRH), which is produced in the hypothalamus ...

  3. Jostel's TSH index - Wikipedia

    en.wikipedia.org/wiki/Jostel's_TSH_index

    Jostel's TSH index (TSHI or JTI), also referred to as Jostel's thyrotropin index or Thyroid Function index (TFI), is a method for estimating the thyrotropic (i.e. thyroid stimulating) function of the anterior pituitary lobe in a quantitative way. [1] [2] The equation has been derived from the logarithmic standard model of thyroid homeostasis.

  4. TRH stimulation test - Wikipedia

    en.wikipedia.org/wiki/TRH_stimulation_test

    Prior to the availability of sensitive TSH assays, thyrotropin releasing hormone or TRH stimulation tests were relied upon for confirming and assessing the degree of suppression in suspected hyperthyroidism. Typically, this stimulation test involves determining basal TSH levels and levels 15 to 30 minutes after an intravenous bolus of TRH ...

  5. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    The hypothalamus secretes TRH (green), which stimulates the pituitary gland to produce TSH (red). This, in turn, stimulates the production of thyroxine by the thyroid (blue). Thyroxine levels decrease TRH and TSH production by a negative feedback process. Thyroid hormone is required for the normal functioning of numerous tissues in the body.

  6. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [1]

  7. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    TSH levels are determined by a classic negative feedback system in which high levels of T3 and T4 suppress the production of TSH, and low levels of T3 and T4 increase the production of TSH. TSH levels are thus often used by doctors as a screening test, where the first approach is to determine whether TSH is elevated, suppressed, or normal. [25 ...

  8. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH from hypothalamus and TSH from anterior pituitary gland.

  9. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...

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