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Upon entering the digestive tract from the bile, cestocidal activity is exhibited. Following exposure to praziquantel, the tapeworm loses its ability to resist digestion by the mammalian host. Because of this, whole tapeworms, including the scolices (plural of "scolex"), are very rarely passed after administration of praziquantel. In many ...
The standard treatment for diphyllobothriasis (as well as many other tapeworm infections) is a single dose of praziquantel, 5–10 mg/kg orally once for both adults and children. [16] [17] [18] Praziquantel is not FDA-approved for this indication. [16] Praziquantel has few side effects, many of which are similar to the symptoms of ...
The two drugs that have been well-described for the treatment of hymenolepiasis are praziquantel and niclosamide. Praziquantel, which is parasiticidal in a single dose for all the stages of the parasite, is the drug of choice because it acts very rapidly against H. nana. Although structurally unrelated to other anthelminthics, it kills both ...
The prescription drug Praziquantel is usually prescribed in a single dose to patients infected with H.nana. Praziquantel is widely used and preferred due to its high efficacy. Research has shown that the cysticercoid phase of H.nana's life cycle is the most susceptible to the Praziquantel treatment. [2]
In animals, infections with Spirometra species can be treated with praziquantel at 30-35 mg/kg, PO of SQ, for 2 consecutive days. [12] Mebendazole at 11 mg/kg, PO, has also been successful. Taking an infected animal to a vet is the best option for ridding a pet of any developmental stage. [12]
Commercially, praziquantel (such as Ezotec® 10 at the dosage of 6.00 mg/kg of body weight, in a single dose) is the drug of choice. It is 100% effective at 10 mg/kg and is well tolerated by chickens, and treated birds showed no clinical complications at various doses tested. [ 9 ]
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