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  2. Steroidal aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Steroidal_aromatase_inhibitor

    The synthesis of exemestane also consists of three steps, as shown in figure 3. First off, a Vilsmeier-Haack reagent is prepared by refluxing paraformaldehyde and dimethylamine hydrochloride in isopentanol at a temperature of 131 °C while removing water from the isopentanol using a Dean-Stark separator. The internal temperature of the reagent ...

  3. Exemestane - Wikipedia

    en.wikipedia.org/wiki/Exemestane

    4-Androstenedione for comparison. Exemestane is known chemically as 6-methylideneandrosta-1,4-diene-3,17-dione. Like the aromatase inhibitors formestane and atamestane, exemestane is a steroid that is structurally similar to 4-androstenedione, the natural substrate of aromatase. It is distinguished from the natural substance only by the ...

  4. Estrogen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Estrogen_deprivation_therapy

    Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.

  5. What is Anastrozole? The breast cancer drug that can cut risk ...

    www.aol.com/news/anastrozole-breast-cancer-drug...

    Women post-menopause with ‘strong family history’ of breast cancer encouraged speak to GP about drug, expert says

  6. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...

  7. Antiestrogen - Wikipedia

    en.wikipedia.org/wiki/Antiestrogen

    Antiestrogens include selective estrogen receptor modulators (SERMs) like tamoxifen, clomifene, and raloxifene, the ER silent antagonist and selective estrogen receptor degrader (SERD) fulvestrant, [6] [7] aromatase inhibitors (AIs) like anastrozole, and antigonadotropins including androgens/anabolic steroids, progestogens, and GnRH analogues.

  8. AOL

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    The search engine that helps you find exactly what you're looking for. Find the most relevant information, video, images, and answers from all across the Web.

  9. Anastrozole - Wikipedia

    en.wikipedia.org/wiki/Anastrozole

    Anastrozole was patented in 1987 and was approved for medical use in 1995. [8] [9] It is on the World Health Organization's List of Essential Medicines. [10] Anastrozole is available as a generic medication. [7] In 2022, it was the 179th most commonly prescribed medication in the United States, with more than 2 million prescriptions. [11] [12]

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