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  2. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/gout-guide-symptoms-treatment...

    Uric acid is a normal waste product made by the body, but in some people, it can accumulate at higher levels and lead to gout. Gout can be divided into four stages: Hyperuricemia.

  3. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

  4. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones . Thus, use of these drugs is contraindicated in persons already with a high urine concentration of uric acid ( hyperuricosuria ).

  5. Uric acid - Wikipedia

    en.wikipedia.org/wiki/Uric_acid

    Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]

  6. Thiazide - Wikipedia

    en.wikipedia.org/wiki/Thiazide

    Hypokalemia – Thiazide diuretics reduce potassium concentration in blood through two indirect mechanisms: inhibition of sodium-chloride symporter at distal convoluted tubule of a nephron and stimulation of aldosterone that activates Na+/K+-ATPase at collecting duct. Inhibition of sodium-chloride symporter increases availability of sodium and ...

  7. Best Stock to Buy Right Now: Uber vs. Lyft - AOL

    www.aol.com/best-stock-buy-now-uber-010500620.html

    The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Uber Technologies wasn’t one of them. The 10 stocks that made ...

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