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HER2-positive breast cancer, stomach cancer (orphan) and oesophageal cancer (orphan). Diarrhoea, interstitial lung disease (uncommon), hepatotoxicity (uncommon) and anaphylaxis (rare). Nilotinib: PO: Bcr-Abl kinase inhibitor. Chronic myeloid leukaemia.
A 2015 Cochrane review found unclear usefulness for cancer pain, [44] though other reviews have found tentative evidence of benefit. [45] [46] It is of unclear effect in hot flashes in people with breast cancer. [47] The effects of aromatherapy are unclear with no peer-reviewed research in regards to cancer treatment. [48]
Decreasing the acid in the stomach can aid the healing of duodenal ulcers and reduce the pain from indigestion and heartburn. However, stomach acids are needed to digest proteins, vitamin B 12 , calcium, and other nutrients, and too little stomach acid causes the condition hypochlorhydria .
The exact medications recommended will vary by country and the individual treatment center, but the following gives an example of the WHO approach to treating chronic pain with medications. If, at any point, treatment fails to provide adequate pain relief, then the doctor and patient move onto the next step. [citation needed]
A painting from 1681 depicting a person affected by nausea and vomiting. Cancer and nausea are associated in about fifty percent of people affected by cancer. [1] This may be as a result of the cancer itself, or as an effect of the treatment such as chemotherapy, radiation therapy, or other medication such as opiates used for pain relief.
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
One study [25] found that infection was the cause of pain in four percent of nearly 300 people with cancer who were referred for pain relief. Another report described seven people with cancer, whose previously well-controlled pain escalated significantly over several days. Antibiotic treatment produced pain relief in all of them within three days.
Pain following surgery can be significant, and many people require strong pain medications such as opioids. There is some low-certainty evidence that starting NSAID painkiller medications in adults early, before surgery, may help reduce post-operative pain, and also reduce the dose or quantity of opioid medications required after surgery. [ 29 ]
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