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  2. Orexin - Wikipedia

    en.wikipedia.org/wiki/Orexin

    Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...

  3. Orexin-A - Wikipedia

    en.wikipedia.org/wiki/Orexin-A

    The rhesus monkeys were split into a test group and into a control group. The test group was administered orexin-A, intravenously or nasally. The control group was given a placebo. The sleep-deprived monkeys which were given the nasal form of orexin-A performed far better than the ones treated with injections.

  4. Narcolepsy - Wikipedia

    en.wikipedia.org/wiki/Narcolepsy

    Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]

  5. How to answer questions about your body this holiday season ...

    www.aol.com/answer-questions-body-holiday-season...

    Or, if you aren't on a weight loss journey or don't wish to entertain conversations about your body, remind yourself that your body is yours—and yours alone. Know your boundaries.

  6. Can Weight Loss Drugs Make You Boring? Doctors Explain ...

    www.aol.com/lifestyle/weight-loss-drugs-boring...

    We know that GLP-1s work across the body and the brain to result in weight loss and that they tamper spikes of feel-good chemicals like dopamine, she says.

  7. Cataplexy - Wikipedia

    en.wikipedia.org/wiki/Cataplexy

    Nevertheless, after giving this treatment to a patient with undetectable orexin levels in the cerebrospinal fluid after only 15 days after the disease onset, the cataplexy was improved and the orexin levels started to normalise. [17] Plasmapheresis: should be similar with IVIgs but it is more invasive and for it even less data is available. [16]

  8. Your Body Never Forgets Muscle. So Here's How Long It ... - AOL

    www.aol.com/body-never-forgets-muscle-heres...

    Mastering high-level skills like an olympic weightlifting move or a golf swing may require up to 10,000 hours of practice, but most people can achieve some level of proficiency in far less time ...

  9. Orexin receptor - Wikipedia

    en.wikipedia.org/wiki/Orexin_receptor

    Both orexin receptors exhibit a similar pharmacology – the 2 orexin peptides, orexin-A and orexin-B, bind to both receptors and, in each case, agonist binding results in an increase in intracellular calcium levels. However, orexin-B shows a 5- to 10-fold selectivity for orexin receptor type 2, whilst orexin-A is equipotent at both receptors.