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Pituitary gland dysfunction can occur from tumors, infections, surgeries, or for other reasons. When the pituitary gland doesn’t produce LH and FSH, there’s no signaling from the brain to the ...
Pituitary adenomas are tumors that occur in the pituitary gland. Most pituitary tumors are benign, approximately 35% are invasive and just 0.1% to 0.2% are carcinomas. [1] Pituitary adenomas represent from 10% to 25% of all intracranial neoplasms, with an estimated prevalence rate in the general population of approximately 17%. [1] [2]
Many pituitary tumors (25%) are found to have areas of hemorrhagic infarction on MRI scans, but apoplexy is not said to exist unless it is accompanied by symptoms. [ 1 ] [ 4 ] In some instances, lumbar puncture may be required if there is a suspicion that the symptoms might be caused by other problems ( meningitis or subarachnoid hemorrhage ).
Treatment of macroorchidism depends on pathogenesis. Surgical removal of the tumor is the most important and advised option for treating macroorchidism caused by non-functioning pituitary macroadenoma. [12] A non-functioning pituitary adenoma is a kind of benign tumor that does not secrete active hormones, and is from the pituitary gland. [13]
The treatment requires frequent monitoring to the 1 in 30,000 that suffer from MEN-1. [3] Endocrine pancreatic tumor are treated with surgery and cytotoxic drugs in case of malignant disease. Pituitary tumors are treated with surgery (acromegaly and Mb. Cushing) or medicine (prolactinomas). [3]
The signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but often specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, and the ideal treatment ...
For instance, symptoms such as loss of libido and sexual dysfunction are subtle, arise gradually, and may falsely indicate a different cause. [11] Many men with pituitary tumor–associated hyperprolactinemia may forego clinical help until they begin to experience serious endocrine and vision complications, such as major headaches or eye ...
Most alternative cancer treatments have not been tested in proper clinical trials. Among studies that have been published, the quality is often poor. A 2006 review of 196 clinical trials that studied unconventional cancer treatments found a lack of early-phase testing, little rationale for dosing regimens, and poor statistical analyses. [11]
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