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Mesotrione is a selective herbicide used mainly in maize crops. [1] It is a synthetic compound inspired by the natural substance leptospermone found in the bottlebrush tree Callistemon citrinus . It inhibits the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD) [ 3 ] and is sold under brand names including Callisto and Tenacity.
The herbicide is usually applied to the soil in which the crop is growing, before the emergence of the weeds. [1] In the US it is applied almost exclusively in corn with annual use in 2018 about 600,000 pounds (270,000 kg). [12] The compound is often formulated in combination with the herbicide safener, cyprosulfamide. [13]
The Herbicide Resistance Action Committee (HRAC) classifies herbicides by their mode of action (MoA) to provide a uniform way for farmers and growers to identify the agents they use and better manage pesticide resistance around the world. [1] [2] It is run by CropLife International [3] in conjunction with the Weed Science Society of America ...
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The industry-sponsored Herbicide Resistance Action Committee (HRAC) advises on the use of herbicides in crop protection and classifies the available compounds according to their chemical structures and mechanism of action so as to manage the risks of pesticide resistance developing. [4]
Mesotrione was introduced in 2002 and like sulcotrione is a triketone, so it is effective on the same weeds and crops, but is more potent, making it more useful in mixes with other herbicides - an important factor for fully controlling weeds and preventing the development of resistance. It has become the biggest selling member of the HPPD class ...
The use of DCPA as a herbicide was first described in a patent filed in 1958. [12] The material was prepared as had been described in a 1948 research paper by treating terephthaloyl chloride with chlorine to give tetrachloroterephthaloyl chloride which was then esterified with methanol. [13] C 6 H 4 (COCl) 2 + 4 Cl 2 + Fe (cat.) → C 6 Cl 4 ...
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