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The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side effect. [9] Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
Hair loss is a well-known side effect of many chemotherapy drugs used to treat certain forms of cancer. Similar to other toxins that cause hair loss, hair loss from cancer medications usually isn ...
[12] [25] As with all chemotherapy, adverse effects are common, and many side effects have been documented. [17] [19] Because docetaxel is a cell-cycle-specific agent, it is cytotoxic to all dividing cells in the body. [26] This includes tumour cells as well as hair follicles, bone marrow and other germ cells.
Hair loss (alopecia) can be caused by chemotherapy that kills rapidly dividing cells; other medications may cause hair to thin. These are most often temporary effects: hair usually starts to regrow a few weeks after the last treatment, but sometimes with a change in color, texture, thickness or style.
Common side effects include hair loss, vomiting, blood in the urine, infections, and kidney problems. [2] Other severe side effects include bone marrow suppression and decreased level of consciousness. [2] Use during pregnancy will likely result in harm to the baby. [2] Ifosfamide is in the alkylating agent and nitrogen mustard family of ...
The most common side effects include alopecia (hair loss), nausea, diarrhea, anemia (reduced number of red blood cells) and asthenia (lack of energy). [5] [8] [3] It can cause worsening of chemotherapy induced neutropenia (low level of white blood cells). [5] It may cause harm to a developing fetus or a newborn baby. [5]
Cyclophosphamide (CP), also known as cytophosphane among other names, [3] is a medication used as chemotherapy and to suppress the immune system. [4] As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. [4]
Vinblastine is a vinca alkaloid [9] [2] [10] and a chemical analogue of vincristine. [11] [12] It binds tubulin, thereby inhibiting the assembly of microtubules. [13]Vinblastine treatment causes M phase specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle and the kinetochore, each of which are necessary for the separation of chromosomes ...
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